Host-microbe interactions is a research area that focuses on the interactions between a host organism and its associated microbiota, which includes bacteria, viruses, fungi, and other microorganisms. These interactions can have profound effects on the health and disease susceptibility of the host, as microorganisms play a key role in maintaining immune system function, nutrient metabolism, and overall homeostasis within the host. Research in this area seeks to understand how these interactions are established, maintained, and disrupted, with the ultimate goal of developing new strategies to manipulate the microbiota for therapeutic purposes. Topics of study in this field include the role of the microbiota in the development of chronic diseases, such as obesity, inflammatory bowel disease, and autoimmune disorders, as well as the impact of microbial communities on host physiology, behavior, and evolution.